Difference between revisions of "YPL172C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006093 YPL172C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''COX10 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''COX10 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XVI:225740..224352 | |nowrap| Chr XVI:225740..224352 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006093 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YPL172C:''' Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders<ref name='S000051293'>Glerum DM and Tzagoloff A (1994) Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant. Proc Natl Acad Sci U S A 91(18):8452-6 {{SGDpaper|S000051293}} PMID 8078902</ref><ref name='S000041456'>Valnot I, et al. (2000) A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency. Hum Mol Genet 9(8):1245-9 |
{{SGDpaper|S000041456}} PMID 10767350</ref> | {{SGDpaper|S000041456}} PMID 10767350</ref> | ||
<br> | <br> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL172C |
| Gene name | COX10 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:225740..224352 |
| Primary SGDID | S000006093 |
Description of YPL172C: Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders[1][2]
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References
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- ↑ Glerum DM and Tzagoloff A (1994) Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant. Proc Natl Acad Sci U S A 91(18):8452-6 SGD PMID 8078902
- ↑ Valnot I, et al. (2000) A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency. Hum Mol Genet 9(8):1245-9 SGD PMID 10767350
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