Difference between revisions of "YIL043C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YIL043C YIL043C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001305 YIL043C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CBR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''CBR1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr IX:274925..274071
 
|nowrap| Chr IX:274925..274071
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001305
 
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'''Description of {{PAGENAME}}:''' Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia<ref name='S000119499'>Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 {{SGDpaper|S000119499}} PMID 17082011</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000062023'>Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 {{SGDpaper|S000062023}} PMID 8307010</ref><ref name='S000062022'>Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem (Tokyo) 81(1):187-95
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'''Description of YIL043C:''' Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia<ref name='S000119499'>Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 {{SGDpaper|S000119499}} PMID 17082011</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000062023'>Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 {{SGDpaper|S000062023}} PMID 8307010</ref><ref name='S000062022'>Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem (Tokyo) 81(1):187-95
 
  {{SGDpaper|S000062022}} PMID 14930</ref>
 
  {{SGDpaper|S000062022}} PMID 14930</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:45, 27 February 2007

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Systematic name YIL043C
Gene name CBR1
Aliases CBR5
Feature type ORF, Verified
Coordinates Chr IX:274925..274071
Primary SGDID S000001305


Description of YIL043C: Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia[1][2][3][4]




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References

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  1. Nussenzveig RH, et al. (2006) A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica 91(11):1542-5 SGD PMID 17082011
  2. Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
  3. Csukai M, et al. (1994) Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae. Eur J Biochem 219(1-2):441-8 SGD PMID 8307010
  4. Kubota S, et al. (1977) Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase. J Biochem (Tokyo) 81(1):187-95 SGD PMID 14930

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