Difference between revisions of "YNL104C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YNL104C
Gene name LEU4
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:426756..424897


Description of YNL104C: Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway[1][2]




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References

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  1. Drain P and Schimmel P (1988) Multiple new genes that determine activity for the first step of leucine biosynthesis in Saccharomyces cerevisiae. Genetics 119(1):13-20 SGD PMID 3294097
  2. Beltzer JP, et al. (1988) Yeast LEU4 encodes mitochondrial and nonmitochondrial forms of alpha-isopropylmalate synthase. J Biol Chem 263(1):368-74 SGD PMID 3275644

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