Difference between revisions of "YLR237W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YLR237W
Gene name THI7
Aliases THI10
Feature type ORF, Verified
Coordinates Chr XII:612369..614165


Description of YLR237W: Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia[1][2]




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References

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  1. Stagg AR, et al. (1999) Defective high-affinity thiamine transporter leads to cell death in thiamine-responsive megaloblastic anemia syndrome fibroblasts. J Clin Invest 103(5):723-9 SGD PMID 10074490
  2. Singleton CK (1997) Identification and characterization of the thiamine transporter gene of Saccharomyces cerevisiae. Gene 199(1-2):111-21 SGD PMID 9358046

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