Difference between revisions of "YER101C"
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| − | '''Description of YER101C:''' | + | '''Description of YER101C:''' Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000040210'>Chang A and Fink GR (1995) Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J Cell Biol 128(1-2):39-49 {{SGDpaper|S000040210}} PMID 7822420</ref><ref name='S000120969'>Riveros-Rosas H, et al. (2003) Diversity, taxonomy and evolution of medium-chain dehydrogenase/reductase superfamily. Eur J Biochem 270(16):3309-34 {{SGDpaper|S000120969}} PMID 12899689</ref><ref name='S000073348'>SGD (2007) Information without a citation in SGD |
{{SGDpaper|S000073348}} PMID </ref> | {{SGDpaper|S000073348}} PMID </ref> | ||
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Latest revision as of 14:05, 12 September 2012
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| Systematic name | YER101C |
| Gene name | AST2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:361794..360502 |
| Primary SGDID | S000000903 |
Description of YER101C: Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication[1][2][3][4]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Chang A and Fink GR (1995) Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J Cell Biol 128(1-2):39-49 SGD PMID 7822420
- ↑ Riveros-Rosas H, et al. (2003) Diversity, taxonomy and evolution of medium-chain dehydrogenase/reductase superfamily. Eur J Biochem 270(16):3309-34 SGD PMID 12899689
- ↑ SGD (2007) Information without a citation in SGD SGD PMID
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