Difference between revisions of "YEL056W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YEL056W
Gene name HAT2
Aliases
Feature type ORF, Verified
Coordinates Chr V:47168..48373


Description of YEL056W: Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing[1][2][3]




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References

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  1. Kelly TJ, et al. (2000) Type B histone acetyltransferase Hat1p participates in telomeric silencing. Mol Cell Biol 20(19):7051-8 SGD PMID 10982821
  2. Parthun MR, et al. (1996) The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell 87(1):85-94 SGD PMID 8858151
  3. Ruiz-Garcia AB, et al. (1998) HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4. J Biol Chem 273(20):12599-605 SGD PMID 9575221

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