Difference between revisions of "YDR308C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YDR308C
Gene name SRB7
Aliases MED21
Feature type ORF, Verified
Coordinates Chr IV:1078445..1078023


Description of YDR308C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p[1][2][3]




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References

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  1. Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
  2. Gromoller A and Lehming N (2000) Srb7p is a physical and physiological target of Tup1p. EMBO J 19(24):6845-52 SGD PMID 11118219
  3. Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910 SGD PMID 7774808

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