Difference between revisions of "YOR004W"

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'''Description of YOR004W:''' Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function<ref name='S000116956'>Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9
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'''Description of YOR004W:''' Component of the small subunit processome, involved in 40S ribosomal subunit biogenesis; interacts with snR30 and is required for dissociation of snR30 from large pre-ribosomal particles; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function; essential protein<ref name='S000116956'>Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9 {{SGDpaper|S000116956}} PMID 16769905</ref><ref name='S000147881'>Hoareau-Aveilla C, et al. (2011) Utp23p is required for dissociation of snR30 small nucleolar RNP from preribosomal particles. Nucleic Acids Res ()
  {{SGDpaper|S000116956}} PMID 16769905</ref>
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  {{SGDpaper|S000147881}} PMID 22180534</ref>
 
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Latest revision as of 14:05, 2 February 2012

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Systematic name YOR004W
Gene name UTP23
Aliases
Feature type ORF, Verified
Coordinates Chr XV:333592..334356
Primary SGDID S000005530


Description of YOR004W: Component of the small subunit processome, involved in 40S ribosomal subunit biogenesis; interacts with snR30 and is required for dissociation of snR30 from large pre-ribosomal particles; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function; essential protein[1][2]




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References

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  1. Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9 SGD PMID 16769905
  2. Hoareau-Aveilla C, et al. (2011) Utp23p is required for dissociation of snR30 small nucleolar RNP from preribosomal particles. Nucleic Acids Res () SGD PMID 22180534

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