Difference between revisions of "YOR122C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR122C YOR122C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005648 YOR122C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PFY1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PFY1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:552888..552299
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|nowrap| Chr XV:552887..552298
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005648
 
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'''Description of {{PAGENAME}}:''' Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, plays a role in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol<ref name='S000058008'>Yeh J and Haarer BK (1996) Profilin is required for the normal timing of actin polymerization in response to thermal stress. FEBS Lett 398(2-3):303-7 {{SGDpaper|S000058008}} PMID 8977127</ref><ref name='S000049891'>Ostrander DB, et al. (1995) Regulation of profilin localization in Saccharomyces cerevisiae by phosphoinositide metabolism. J Biol Chem 270(45):27045-50
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'''Description of YOR122C:''' Profilin, binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress<ref name='S000058355'>Eads JC, et al. (1998) Structure determination and characterization of Saccharomyces cerevisiae profilin. Biochemistry 37(32):11171-81 {{SGDpaper|S000058355}} PMID 9698363</ref><ref name='S000049891'>Ostrander DB, et al. (1995) Regulation of profilin localization in Saccharomyces cerevisiae by phosphoinositide metabolism. J Biol Chem 270(45):27045-50 {{SGDpaper|S000049891}} PMID 7592954</ref><ref name='S000058008'>Yeh J and Haarer BK (1996) Profilin is required for the normal timing of actin polymerization in response to thermal stress. FEBS Lett 398(2-3):303-7
  {{SGDpaper|S000049891}} PMID 7592954</ref>
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  {{SGDpaper|S000058008}} PMID 8977127</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOR122C
Gene name PFY1
Aliases PRF1
Feature type ORF, Verified
Coordinates Chr XV:552887..552298
Primary SGDID S000005648


Description of YOR122C: Profilin, binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress[1][2][3]




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References

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  1. Eads JC, et al. (1998) Structure determination and characterization of Saccharomyces cerevisiae profilin. Biochemistry 37(32):11171-81 SGD PMID 9698363
  2. Ostrander DB, et al. (1995) Regulation of profilin localization in Saccharomyces cerevisiae by phosphoinositide metabolism. J Biol Chem 270(45):27045-50 SGD PMID 7592954
  3. Yeh J and Haarer BK (1996) Profilin is required for the normal timing of actin polymerization in response to thermal stress. FEBS Lett 398(2-3):303-7 SGD PMID 8977127

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