Difference between revisions of "YMR039C"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YMR039C YMR039C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004642 YMR039C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SUB1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SUB1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:349521..348643
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|nowrap| Chr XIII:349522..348644
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004642
 
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'''Description of {{PAGENAME}}:''' Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations<ref name='S000080771'>Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 {{SGDpaper|S000080771}} PMID 15692559</ref><ref name='S000076738'>Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93
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'''Description of YMR039C:''' Transcriptional coactivator, facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes<ref name='S000080771'>Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 {{SGDpaper|S000080771}} PMID 15692559</ref><ref name='S000129320'>Rosonina E, et al. (2009) Sub1 Functions in Osmoregulation and in Transcription by both RNA Polymerases II and III. Mol Cell Biol 29(8):2308-21 {{SGDpaper|S000129320}} PMID 19204085</ref><ref name='S000076738'>Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93
 
  {{SGDpaper|S000076738}} PMID 15199162</ref>
 
  {{SGDpaper|S000076738}} PMID 15199162</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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<!--
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YMR039C
Gene name SUB1
Aliases TSP1
Feature type ORF, Verified
Coordinates Chr XIII:349522..348644
Primary SGDID S000004642


Description of YMR039C: Transcriptional coactivator, facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes[1][2][3]




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References

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  1. Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 SGD PMID 15692559
  2. Rosonina E, et al. (2009) Sub1 Functions in Osmoregulation and in Transcription by both RNA Polymerases II and III. Mol Cell Biol 29(8):2308-21 SGD PMID 19204085
  3. Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93 SGD PMID 15199162

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