Difference between revisions of "YLR237W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR237W YLR237W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004227 YLR237W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''THI7 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''THI7 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:612369..614165
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|nowrap| Chr XII:612367..614163
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004227
 
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'''Description of {{PAGENAME}}:''' Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia<ref name='S000065392'>Stagg AR, et al. (1999) Defective high-affinity thiamine transporter leads to cell death in thiamine-responsive megaloblastic anemia syndrome fibroblasts. J Clin Invest 103(5):723-9 {{SGDpaper|S000065392}} PMID 10074490</ref><ref name='S000046882'>Singleton CK (1997) Identification and characterization of the thiamine transporter gene of Saccharomyces cerevisiae. Gene 199(1-2):111-21
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'''Description of YLR237W:''' Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia<ref name='S000052268'>Enjo F, et al. (1997) Isolation and characterization of a thiamin transport gene, THI10, from Saccharomyces cerevisiae. J Biol Chem 272(31):19165-70 {{SGDpaper|S000052268}} PMID 9235906</ref><ref name='S000046882'>Singleton CK (1997) Identification and characterization of the thiamine transporter gene of Saccharomyces cerevisiae. Gene 199(1-2):111-21 {{SGDpaper|S000046882}} PMID 9358046</ref><ref name='S000065392'>Stagg AR, et al. (1999) Defective high-affinity thiamine transporter leads to cell death in thiamine-responsive megaloblastic anemia syndrome fibroblasts. J Clin Invest 103(5):723-9
  {{SGDpaper|S000046882}} PMID 9358046</ref>
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  {{SGDpaper|S000065392}} PMID 10074490</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLR237W
Gene name THI7
Aliases THI10
Feature type ORF, Verified
Coordinates Chr XII:612367..614163
Primary SGDID S000004227


Description of YLR237W: Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia[1][2][3]




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References

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  1. Enjo F, et al. (1997) Isolation and characterization of a thiamin transport gene, THI10, from Saccharomyces cerevisiae. J Biol Chem 272(31):19165-70 SGD PMID 9235906
  2. Singleton CK (1997) Identification and characterization of the thiamine transporter gene of Saccharomyces cerevisiae. Gene 199(1-2):111-21 SGD PMID 9358046
  3. Stagg AR, et al. (1999) Defective high-affinity thiamine transporter leads to cell death in thiamine-responsive megaloblastic anemia syndrome fibroblasts. J Clin Invest 103(5):723-9 SGD PMID 10074490

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