Difference between revisions of "YLR189C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR189C YLR189C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004179 YLR189C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG26 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''ATG26 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:534395..530799
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|nowrap| Chr XII:534393..530797
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004179
 
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'''Description of {{PAGENAME}}:''' UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy<ref name='S000074141'>Klionsky DJ, et al. (2003) A unified nomenclature for yeast autophagy-related genes. Dev Cell 5(4):539-45 {{SGDpaper|S000074141}} PMID 14536056</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000045791'>Warnecke D, et al. (1999) Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum. J Biol Chem 274(19):13048-59
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'''Description of YLR189C:''' UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy<ref name='S000119106'>Cao Y and Klionsky DJ (2007) Atg26 is not involved in autophagy-related pathways in Saccharomyces cerevisiae. Autophagy 3(1):17-20 {{SGDpaper|S000119106}} PMID 17012830</ref><ref name='S000074141'>Klionsky DJ, et al. (2003) A unified nomenclature for yeast autophagy-related genes. Dev Cell 5(4):539-45 {{SGDpaper|S000074141}} PMID 14536056</ref><ref name='S000045791'>Warnecke D, et al. (1999) Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum. J Biol Chem 274(19):13048-59
 
  {{SGDpaper|S000045791}} PMID 10224056</ref>
 
  {{SGDpaper|S000045791}} PMID 10224056</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLR189C
Gene name ATG26
Aliases UGT51
Feature type ORF, Verified
Coordinates Chr XII:534393..530797
Primary SGDID S000004179


Description of YLR189C: UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy[1][2][3]




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References

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  1. Cao Y and Klionsky DJ (2007) Atg26 is not involved in autophagy-related pathways in Saccharomyces cerevisiae. Autophagy 3(1):17-20 SGD PMID 17012830
  2. Klionsky DJ, et al. (2003) A unified nomenclature for yeast autophagy-related genes. Dev Cell 5(4):539-45 SGD PMID 14536056
  3. Warnecke D, et al. (1999) Cloning and functional expression of UGT genes encoding sterol glucosyltransferases from Saccharomyces cerevisiae, Candida albicans, Pichia pastoris, and Dictyostelium discoideum. J Biol Chem 274(19):13048-59 SGD PMID 10224056

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