Difference between revisions of "YGL093W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGL093W YGL093W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003061 YGL093W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPC105 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPC105 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:334889..337642
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|nowrap| Chr VII:334886..337639
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003061
 
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'''Description of {{PAGENAME}}:''' Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp<ref name='S000075232'>Nekrasov VS, et al. (2003) Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(12):4931-46 {{SGDpaper|S000075232}} PMID 14565975</ref><ref name='S000047788'>Wigge PA, et al. (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77
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'''Description of YGL093W:''' Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components<ref name='S000075232'>Nekrasov VS, et al. (2003) Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(12):4931-46 {{SGDpaper|S000075232}} PMID 14565975</ref><ref name='S000132197'>Pagliuca C, et al. (2009) Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. PLoS One 4(10):e7640
  {{SGDpaper|S000047788}} PMID 9585415</ref>
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  {{SGDpaper|S000132197}} PMID 19893618</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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<!--
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL093W
Gene name SPC105
Aliases
Feature type ORF, Verified
Coordinates Chr VII:334886..337639
Primary SGDID S000003061


Description of YGL093W: Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components[1][2]




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References

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  1. Nekrasov VS, et al. (2003) Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(12):4931-46 SGD PMID 14565975
  2. Pagliuca C, et al. (2009) Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. PLoS One 4(10):e7640 SGD PMID 19893618

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