Difference between revisions of "YDL127W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDL127W YDL127W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002285 YDL127W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PCL2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PCL2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr IV:234927..235853
 
|nowrap| Chr IV:234927..235853
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002285
 
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'''Description of {{PAGENAME}}:''' G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to entry into the mitotic cell cycle, essential for cell morphogenesis; localizes to sites of polarized cell growth<ref name='S000075020'>Moffat J and Andrews B (2004) Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast. Nat Cell Biol 6(1):59-66 {{SGDpaper|S000075020}} PMID 14688790</ref><ref name='S000058300'>Aerne BL, et al. (1998) Swi5 controls a novel wave of cyclin synthesis in late mitosis. Mol Biol Cell 9(4):945-56 {{SGDpaper|S000058300}} PMID 9529390</ref><ref name='S000049533'>Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23 {{SGDpaper|S000049533}} PMID 9032248</ref><ref name='S000048383'>Measday V, et al. (1994) The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast. Science 266(5189):1391-5 {{SGDpaper|S000048383}} PMID 7973731</ref><ref name='S000047939'>Colwill K, et al. (1999) In vivo analysis of the domains of yeast Rvs167p suggests Rvs167p function is mediated through multiple protein interactions. Genetics 152(3):881-93
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'''Description of YDL127W:''' Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth<ref name='S000124059'>Huang D, et al. (2007) Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast. Mol Microbiol 66(2):303-14 {{SGDpaper|S000124059}} PMID 17850263</ref><ref name='S000048383'>Measday V, et al. (1994) The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast. Science 266(5189):1391-5 {{SGDpaper|S000048383}} PMID 7973731</ref><ref name='S000049533'>Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23 {{SGDpaper|S000049533}} PMID 9032248</ref><ref name='S000075020'>Moffat J and Andrews B (2004) Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast. Nat Cell Biol 6(1):59-66
  {{SGDpaper|S000047939}} PMID 10388809</ref>
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  {{SGDpaper|S000075020}} PMID 14688790</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YDL127W
Gene name PCL2
Aliases CLN4
Feature type ORF, Verified
Coordinates Chr IV:234927..235853
Primary SGDID S000002285


Description of YDL127W: Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth[1][2][3][4]




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References

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  1. Huang D, et al. (2007) Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast. Mol Microbiol 66(2):303-14 SGD PMID 17850263
  2. Measday V, et al. (1994) The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast. Science 266(5189):1391-5 SGD PMID 7973731
  3. Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23 SGD PMID 9032248
  4. Moffat J and Andrews B (2004) Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast. Nat Cell Biol 6(1):59-66 SGD PMID 14688790

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