Difference between revisions of "YKL017C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YKL017C YKL017C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001500 YKL017C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HCS1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''HCS1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XI:406884..404833
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|nowrap| Chr XI:407241..405190
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001500
 
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'''Description of {{PAGENAME}}:''' Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities<ref name='S000058490'>Biswas EE, et al. (1993) DNA helicase associated with DNA polymerase alpha: isolation by a modified immunoaffinity chromatography. Biochemistry 32(49):13393-8 {{SGDpaper|S000058490}} PMID 8257676</ref><ref name='S000058225'>Biswas EE, et al. (1997) Yeast DNA helicase A: cloning, expression, purification, and enzymatic characterization. Biochemistry 36(43):13277-84 {{SGDpaper|S000058225}} PMID 9341218</ref><ref name='S000050304'>Biswas SB, et al. (1997) Purification and characterization of DNA polymerase alpha-associated replication protein A-dependent yeast DNA helicase A. Biochemistry 36(43):13270-6
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'''Description of YKL017C:''' Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities<ref name='S000058490'>Biswas EE, et al. (1993) DNA helicase associated with DNA polymerase alpha: isolation by a modified immunoaffinity chromatography. Biochemistry 32(49):13393-8 {{SGDpaper|S000058490}} PMID 8257676</ref><ref name='S000058225'>Biswas EE, et al. (1997) Yeast DNA helicase A: cloning, expression, purification, and enzymatic characterization. Biochemistry 36(43):13277-84 {{SGDpaper|S000058225}} PMID 9341218</ref><ref name='S000050304'>Biswas SB, et al. (1997) Purification and characterization of DNA polymerase alpha-associated replication protein A-dependent yeast DNA helicase A. Biochemistry 36(43):13270-6
 
  {{SGDpaper|S000050304}} PMID 9341217</ref>
 
  {{SGDpaper|S000050304}} PMID 9341217</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YKL017C
Gene name HCS1
Aliases DIP1
Feature type ORF, Verified
Coordinates Chr XI:407241..405190
Primary SGDID S000001500


Description of YKL017C: Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities[1][2][3]




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Community Commentary

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References

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  1. Biswas EE, et al. (1993) DNA helicase associated with DNA polymerase alpha: isolation by a modified immunoaffinity chromatography. Biochemistry 32(49):13393-8 SGD PMID 8257676
  2. Biswas EE, et al. (1997) Yeast DNA helicase A: cloning, expression, purification, and enzymatic characterization. Biochemistry 36(43):13277-84 SGD PMID 9341218
  3. Biswas SB, et al. (1997) Purification and characterization of DNA polymerase alpha-associated replication protein A-dependent yeast DNA helicase A. Biochemistry 36(43):13270-6 SGD PMID 9341217

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