Difference between revisions of "YHR064C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001106 YHR064C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001106 YHR064C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SSZ1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SSZ1 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YHR064C
Gene name SSZ1
Aliases PDR13
Feature type ORF, Verified
Coordinates Chr VIII:227141..225525
Primary SGDID S000001106


Description of YHR064C: Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP[1][2][3]




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References

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  1. Eisenman HC and Craig EA (2004) Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1. Mol Microbiol 53(1):335-44 SGD PMID 15225326
  2. Hallstrom TC and Moye-Rowley WS (2000) Hyperactive forms of the Pdr1p transcription factor fail to respond to positive regulation by the hsp70 protein Pdr13p. Mol Microbiol 36(2):402-13 SGD PMID 10792726
  3. Huang P, et al. (2005) The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1. Nat Struct Mol Biol 12(6):497-504 SGD PMID 15908962

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