Difference between revisions of "YPL172C"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:18, 30 January 2007

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Systematic name YPL172C
Gene name COX10
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:225740..224352


Description of YPL172C: Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders[1][2]




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Community Commentary

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References

See Help:References on how to add references

  1. Glerum DM and Tzagoloff A (1994) Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant. Proc Natl Acad Sci U S A 91(18):8452-6 SGD PMID 8078902
  2. Valnot I, et al. (2000) A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency. Hum Mol Genet 9(8):1245-9 SGD PMID 10767350

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