Difference between revisions of "YPL215W"
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| − | '''Description of YPL215W:''' Mitochondrial protein required for assembly of | + | '''Description of YPL215W:''' Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex<ref name='S000145702'>Gruschke S, et al. (2011) Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol 193(6):1101-14 {{SGDpaper|S000145702}} PMID 21670217</ref><ref name='S000081000'>Kronekova Z and Rodel G (2005) Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae. Curr Genet 47(4):203-12 {{SGDpaper|S000081000}} PMID 15759116</ref><ref name='S000061294'>Shi G, et al. (2001) Identification of functional regions of Cbp3p, an enzyme-specific chaperone required for the assembly of ubiquinol-cytochrome c reductase in yeast mitochondria. Biochim Biophys Acta 1506(2):103-16 |
{{SGDpaper|S000061294}} PMID 11522252</ref> | {{SGDpaper|S000061294}} PMID 11522252</ref> | ||
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Revision as of 14:05, 22 June 2011
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| Systematic name | YPL215W |
| Gene name | CBP3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:147416..148423 |
| Primary SGDID | S000006136 |
Description of YPL215W: Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex[1][2][3]
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References
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- ↑ Gruschke S, et al. (2011) Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol 193(6):1101-14 SGD PMID 21670217
- ↑ Kronekova Z and Rodel G (2005) Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae. Curr Genet 47(4):203-12 SGD PMID 15759116
- ↑ Shi G, et al. (2001) Identification of functional regions of Cbp3p, an enzyme-specific chaperone required for the assembly of ubiquinol-cytochrome c reductase in yeast mitochondria. Biochim Biophys Acta 1506(2):103-16 SGD PMID 11522252
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