Difference between revisions of "YGR032W"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:17, 30 January 2007

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Systematic name YGR032W
Gene name GSC2
Aliases FKS2
Feature type ORF, Verified
Coordinates Chr VII:548268..553955


Description of YGR032W: Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)[1][2][3][4]




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Community Commentary

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References

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  1. Huang LS, et al. (2005) The Smk1p MAP kinase negatively regulates Gsc2p, a 1,3-beta-glucan synthase, during spore wall morphogenesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 102(35):12431-6 SGD PMID 16116083
  2. Mazur P and Baginsky W (1996) In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1. J Biol Chem 271(24):14604-9 SGD PMID 8662910
  3. Inoue SB, et al. (1995) Characterization and gene cloning of 1,3-beta-D-glucan synthase from Saccharomyces cerevisiae. Eur J Biochem 231(3):845-54 SGD PMID 7649185
  4. Mazur P, et al. (1995) Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase. Mol Cell Biol 15(10):5671-81 SGD PMID 7565718

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