Difference between revisions of "YLR421C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:965557..965087
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|nowrap| Chr XII:965560..965090
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004413
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004413

Revision as of 14:05, 3 February 2011

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Systematic name YLR421C
Gene name RPN13
Aliases
Feature type ORF, Verified
Coordinates Chr XII:965560..965090
Primary SGDID S000004413


Description of YLR421C: Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability[1][2][3]




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References

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  1. Husnjak K, et al. (2008) Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 453(7194):481-488 SGD PMID 18497817
  2. Seong KM, et al. (2007) Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome. FEBS Lett 581(13):2567-73 SGD PMID 17499717
  3. Verma R, et al. (2000) Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell 11(10):3425-39 SGD PMID 11029046

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