Difference between revisions of "YOR226C"

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'''Description of YOR226C:''' Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable<ref name='S000041686'>Garland SA, et al. (1999) Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly. J Mol Biol 294(4):897-907 {{SGDpaper|S000041686}} PMID 10588895</ref><ref name='S000045090'>Schilke B, et al. (1999) Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(18):10206-11 {{SGDpaper|S000045090}} PMID 10468587</ref><ref name='S000059064'>Gerber J, et al. (2004) The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. Mol Cell Biol 24(11):4848-57
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'''Description of YOR226C:''' Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable<ref name='S000041686'>Garland SA, et al. (1999) Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly. J Mol Biol 294(4):897-907 {{SGDpaper|S000041686}} PMID 10588895</ref><ref name='S000059064'>Gerber J, et al. (2004) The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. Mol Cell Biol 24(11):4848-57 {{SGDpaper|S000059064}} PMID 15143178</ref><ref name='S000045090'>Schilke B, et al. (1999) Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(18):10206-11
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  {{SGDpaper|S000045090}} PMID 10468587</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YOR226C
Gene name ISU2
Aliases NUA2
Feature type ORF, Verified
Coordinates Chr XV:762085..761615
Primary SGDID S000005752


Description of YOR226C: Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable[1][2][3]




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References

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  1. Garland SA, et al. (1999) Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly. J Mol Biol 294(4):897-907 SGD PMID 10588895
  2. Gerber J, et al. (2004) The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. Mol Cell Biol 24(11):4848-57 SGD PMID 15143178
  3. Schilke B, et al. (1999) Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(18):10206-11 SGD PMID 10468587

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