Difference between revisions of "YPL096W"

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'''Description of YPL096W:''' Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation, localizes to the cytoplasm and nucleus, interacts with the DNA repair protein Rad23p<ref name='S000045805'>Suzuki T, et al. (2000) PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. J Cell Biol 149(5):1039-52 {{SGDpaper|S000045805}} PMID 10831608</ref><ref name='S000079894'>Biswas S, et al. (2004) The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23. Biochem Biophys Res Commun 323(1):149-55
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'''Description of YPL096W:''' Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p<ref name='S000045805'>Suzuki T, et al. (2000) PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. J Cell Biol 149(5):1039-52 {{SGDpaper|S000045805}} PMID 10831608</ref><ref name='S000079894'>Biswas S, et al. (2004) The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23. Biochem Biophys Res Commun 323(1):149-55 {{SGDpaper|S000079894}} PMID 15351714</ref><ref name='S000132732'>Wang S, et al. (2009) N-terminal deletion of Peptide:N-glycanase results in enhanced deglycosylation activity. PLoS One 4(12):e8335
  {{SGDpaper|S000079894}} PMID 15351714</ref>
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  {{SGDpaper|S000132732}} PMID 20016784</ref>
 
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Revision as of 14:05, 3 February 2010

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Systematic name YPL096W
Gene name PNG1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:366924..368015
Primary SGDID S000006017


Description of YPL096W: Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p[1][2][3]




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References

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  1. Suzuki T, et al. (2000) PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. J Cell Biol 149(5):1039-52 SGD PMID 10831608
  2. Biswas S, et al. (2004) The N-terminus of yeast peptide: N-glycanase interacts with the DNA repair protein Rad23. Biochem Biophys Res Commun 323(1):149-55 SGD PMID 15351714
  3. Wang S, et al. (2009) N-terminal deletion of Peptide:N-glycanase results in enhanced deglycosylation activity. PLoS One 4(12):e8335 SGD PMID 20016784

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