Difference between revisions of "YGL093W"

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'''Description of YGL093W:''' Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp<ref name='S000047788'>Wigge PA, et al. (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141(4):967-77 {{SGDpaper|S000047788}} PMID 9585415</ref><ref name='S000075232'>Nekrasov VS, et al. (2003) Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(12):4931-46
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'''Description of YGL093W:''' Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components<ref name='S000075232'>Nekrasov VS, et al. (2003) Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(12):4931-46 {{SGDpaper|S000075232}} PMID 14565975</ref><ref name='S000132197'>Pagliuca C, et al. (2009) Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. PLoS One 4(10):e7640
  {{SGDpaper|S000075232}} PMID 14565975</ref>
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  {{SGDpaper|S000132197}} PMID 19893618</ref>
 
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Revision as of 14:05, 25 November 2009

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Systematic name YGL093W
Gene name SPC105
Aliases
Feature type ORF, Verified
Coordinates Chr VII:334889..337642
Primary SGDID S000003061


Description of YGL093W: Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components[1][2]




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References

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  1. Nekrasov VS, et al. (2003) Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(12):4931-46 SGD PMID 14565975
  2. Pagliuca C, et al. (2009) Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint. PLoS One 4(10):e7640 SGD PMID 19893618

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