Difference between revisions of "YLR192C"
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| − | '''Description of YLR192C:''' Dual function protein involved in translation initiation as a substoichiometric component of | + | '''Description of YLR192C:''' Dual function protein involved in translation initiation as a substoichiometric component (eIF3j) of translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA<ref name='S000048910'>Valasek L, et al. (1999) The Saccharomyces cerevisiae HCR1 gene encoding a homologue of the p35 subunit of human translation initiation factor 3 (eIF3) is a high copy suppressor of a temperature-sensitive mutation in the Rpg1p subunit of yeast eIF3. J Biol Chem 274(39):27567-72 {{SGDpaper|S000048910}} PMID 10488093</ref><ref name='S000060771'>Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 |
{{SGDpaper|S000060771}} PMID 11387228</ref> | {{SGDpaper|S000060771}} PMID 11387228</ref> | ||
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Revision as of 14:05, 2 June 2009
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| Systematic name | YLR192C |
| Gene name | HCR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:539591..538794 |
| Primary SGDID | S000004182 |
Description of YLR192C: Dual function protein involved in translation initiation as a substoichiometric component (eIF3j) of translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA[1][2]
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References
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- ↑ Valasek L, et al. (1999) The Saccharomyces cerevisiae HCR1 gene encoding a homologue of the p35 subunit of human translation initiation factor 3 (eIF3) is a high copy suppressor of a temperature-sensitive mutation in the Rpg1p subunit of yeast eIF3. J Biol Chem 274(39):27567-72 SGD PMID 10488093
- ↑ Phan L, et al. (2001) A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNA(i)Met. EMBO J 20(11):2954-65 SGD PMID 11387228
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