Difference between revisions of "YPL262W"

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'''Description of YPL262W:''' Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria<ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 {{SGDpaper|S000123951}} PMID 17761666</ref><ref name='S000074337'>Sass E, et al. (2003) Folding of fumarase during mitochondrial import determines its dual targeting in yeast. J Biol Chem 278(46):45109-16 {{SGDpaper|S000074337}} PMID 12960177</ref><ref name='S000047064'>Przybyla-Zawislak B, et al. (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66
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'''Description of YPL262W:''' Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria<ref name='S000047064'>Przybyla-Zawislak B, et al. (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66 {{SGDpaper|S000047064}} PMID 10224250</ref><ref name='S000074337'>Sass E, et al. (2003) Folding of fumarase during mitochondrial import determines its dual targeting in yeast. J Biol Chem 278(46):45109-16 {{SGDpaper|S000074337}} PMID 12960177</ref><ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906
  {{SGDpaper|S000047064}} PMID 10224250</ref>
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  {{SGDpaper|S000123951}} PMID 17761666</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YPL262W
Gene name FUM1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:47336..48802
Primary SGDID S000006183


Description of YPL262W: Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria[1][2][3]




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References

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  1. Przybyla-Zawislak B, et al. (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66 SGD PMID 10224250
  2. Sass E, et al. (2003) Folding of fumarase during mitochondrial import determines its dual targeting in yeast. J Biol Chem 278(46):45109-16 SGD PMID 12960177
  3. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666

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