Difference between revisions of "YNL082W"

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'''Description of YNL082W:''' ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL<ref name='S000078165'>Hall MC, et al. (2003) DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. Nucleic Acids Res 31(8):2025-34 {{SGDpaper|S000078165}} PMID 12682353</ref><ref name='S000069240'>Hall MC, et al. (2002) Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins. J Biol Chem 277(5):3673-9 {{SGDpaper|S000069240}} PMID 11717305</ref><ref name='S000040150'>Williamson MS, et al. (1985) Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110(4):609-46
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'''Description of YNL082W:''' ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL<ref name='S000040150'>Williamson MS, et al. (1985) Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110(4):609-46 {{SGDpaper|S000040150}} PMID 3896926</ref><ref name='S000069240'>Hall MC, et al. (2002) Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins. J Biol Chem 277(5):3673-9 {{SGDpaper|S000069240}} PMID 11717305</ref><ref name='S000078165'>Hall MC, et al. (2003) DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. Nucleic Acids Res 31(8):2025-34
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  {{SGDpaper|S000078165}} PMID 12682353</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YNL082W
Gene name PMS1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:473392..476013
Primary SGDID S000005026


Description of YNL082W: ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL[1][2][3]




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References

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  1. Williamson MS, et al. (1985) Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110(4):609-46 SGD PMID 3896926
  2. Hall MC, et al. (2002) Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins. J Biol Chem 277(5):3673-9 SGD PMID 11717305
  3. Hall MC, et al. (2003) DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. Nucleic Acids Res 31(8):2025-34 SGD PMID 12682353

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