Difference between revisions of "YMR190C"
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| − | '''Description of YMR190C:''' Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes<ref name=' | + | '''Description of YMR190C:''' Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes<ref name='S000055270'>Sun H, et al. (1999) The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res 27(9):1978-84 {{SGDpaper|S000055270}} PMID 10198430</ref><ref name='S000081521'>Rockmill B, et al. (2003) The Sgs1 helicase regulates chromosome synapsis and meiotic crossing over. Curr Biol 13(22):1954-62 {{SGDpaper|S000081521}} PMID 14614820</ref><ref name='S000071163'>Huber MD, et al. (2002) G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. Nucleic Acids Res 30(18):3954-61 {{SGDpaper|S000071163}} PMID 12235379</ref><ref name='S000072997'>Versini G, et al. (2003) The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication. EMBO J 22(8):1939-49 |
| − | {{SGDpaper| | + | {{SGDpaper|S000072997}} PMID 12682026</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YMR190C |
| Gene name | SGS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:645257..640914 |
| Primary SGDID | S000004802 |
Description of YMR190C: Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes[1][2][3][4]
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References
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- ↑ Sun H, et al. (1999) The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs. Nucleic Acids Res 27(9):1978-84 SGD PMID 10198430
- ↑ Rockmill B, et al. (2003) The Sgs1 helicase regulates chromosome synapsis and meiotic crossing over. Curr Biol 13(22):1954-62 SGD PMID 14614820
- ↑ Huber MD, et al. (2002) G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition. Nucleic Acids Res 30(18):3954-61 SGD PMID 12235379
- ↑ Versini G, et al. (2003) The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication. EMBO J 22(8):1939-49 SGD PMID 12682026
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