Difference between revisions of "YLR242C"
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| − | '''Description of YLR242C:''' Protein functioning in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein<ref name=' | + | '''Description of YLR242C:''' Protein functioning in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein<ref name='S000059466'>Tinkelenberg AH, et al. (2000) Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1. J Biol Chem 275(52):40667-70 {{SGDpaper|S000059466}} PMID 11063737</ref><ref name='S000071418'>Swain E, et al. (2002) Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1. J Biol Chem 277(39):36152-60 {{SGDpaper|S000071418}} PMID 12145310</ref><ref name='S000125620'>Kajiwara K, et al. (2008) Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum. Mol Biol Cell 19(5):2069-82 |
| − | {{SGDpaper| | + | {{SGDpaper|S000125620}} PMID 18287539</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YLR242C |
| Gene name | ARV1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:623885..622920 |
| Primary SGDID | S000004232 |
Description of YLR242C: Protein functioning in transport of glycosylphosphatidylinositol intermediates into the ER lumen; required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein[1][2][3]
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References
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- ↑ Tinkelenberg AH, et al. (2000) Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1. J Biol Chem 275(52):40667-70 SGD PMID 11063737
- ↑ Swain E, et al. (2002) Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1. J Biol Chem 277(39):36152-60 SGD PMID 12145310
- ↑ Kajiwara K, et al. (2008) Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum. Mol Biol Cell 19(5):2069-82 SGD PMID 18287539
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