Difference between revisions of "YDR320C-A"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1108495..1108277
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|nowrap| Chr IV:1108496..1108278
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000007604
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000007604
 
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'''Description of YDR320C-A:''' Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis<ref name='S000114260'>Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 {{SGDpaper|S000114260}} PMID 16415853</ref><ref name='S000080444'>Miranda JJ, et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12(2):138-43 {{SGDpaper|S000080444}} PMID 15640796</ref><ref name='S000080667'>Westermann S, et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17(2):277-90 {{SGDpaper|S000080667}} PMID 15664196</ref><ref name='S000071581'>Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 {{SGDpaper|S000071581}} PMID 12408861</ref><ref name='S000069052'>Li Y, et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16(2):183-97
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'''Description of YDR320C-A:''' Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis<ref name='S000114260'>Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 {{SGDpaper|S000114260}} PMID 16415853</ref><ref name='S000080667'>Westermann S, et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17(2):277-90 {{SGDpaper|S000080667}} PMID 15664196</ref><ref name='S000080444'>Miranda JJ, et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12(2):138-43 {{SGDpaper|S000080444}} PMID 15640796</ref><ref name='S000071581'>Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 {{SGDpaper|S000071581}} PMID 12408861</ref><ref name='S000069052'>Li Y, et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16(2):183-97
 
  {{SGDpaper|S000069052}} PMID 11799062</ref>
 
  {{SGDpaper|S000069052}} PMID 11799062</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YDR320C-A
Gene name DAD4
Aliases HSK2
Feature type ORF, Verified
Coordinates Chr IV:1108496..1108278
Primary SGDID S000007604


Description of YDR320C-A: Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis[1][2][3][4][5]




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References

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  1. Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 SGD PMID 16415853
  2. Westermann S, et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17(2):277-90 SGD PMID 15664196
  3. Miranda JJ, et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12(2):138-43 SGD PMID 15640796
  4. Cheeseman IM, et al. (2002) Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell 111(2):163-72 SGD PMID 12408861
  5. Li Y, et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev 16(2):183-97 SGD PMID 11799062

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