Difference between revisions of "YMR039C"

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'''Description of YMR039C:''' Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations<ref name='S000080771'>Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 {{SGDpaper|S000080771}} PMID 15692559</ref><ref name='S000076738'>Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93
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'''Description of YMR039C:''' Transcriptional coactivator, facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes<ref name='S000129320'>Rosonina E, et al. (2009) Sub1 functions in osmoregulation and in transcription by both RNA polymerases II and III. Mol Cell Biol {{SGDpaper|S000129320}} PMID 19204085</ref><ref name='S000080771'>Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 {{SGDpaper|S000080771}} PMID 15692559</ref><ref name='S000076738'>Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93
 
  {{SGDpaper|S000076738}} PMID 15199162</ref>
 
  {{SGDpaper|S000076738}} PMID 15199162</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YMR039C
Gene name SUB1
Aliases TSP1
Feature type ORF, Verified
Coordinates Chr XIII:349521..348643
Primary SGDID S000004642


Description of YMR039C: Transcriptional coactivator, facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes[1][2][3]




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References

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  1. Rosonina E, et al. (2009) Sub1 functions in osmoregulation and in transcription by both RNA polymerases II and III. Mol Cell Biol SGD PMID 19204085
  2. Calvo O and Manley JL (2005) The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. EMBO J 24(5):1009-20 SGD PMID 15692559
  3. Wang JY, et al. (2004) The single-strand DNA binding activity of human PC4 prevents mutagenesis and killing by oxidative DNA damage. Mol Cell Biol 24(13):6084-93 SGD PMID 15199162

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