Difference between revisions of "YJL085W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:272822..274693
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|nowrap| Chr X:272821..274692
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003621
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003621
 
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'''Description of YJL085W:''' Essential 70kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis<ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 {{SGDpaper|S000047160}} PMID 8978675</ref><ref name='S000044360'>Robinson NG, et al. (1999) Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70. Mol Cell Biol 19(5):3580-7
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'''Description of YJL085W:''' Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which directs secretory vesicles to active sites of exocytosis; acts with Sec3p in membrane targeting of the exocyst via PI(4,5)P2 binding<ref name='S000126304'>He B, et al. (2007) Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J 26(18):4053-65 {{SGDpaper|S000126304}} PMID 17717527</ref><ref name='S000047160'>TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 {{SGDpaper|S000047160}} PMID 8978675</ref><ref name='S000044360'>Robinson NG, et al. (1999) Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70. Mol Cell Biol 19(5):3580-7
 
  {{SGDpaper|S000044360}} PMID 10207081</ref>
 
  {{SGDpaper|S000044360}} PMID 10207081</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YJL085W
Gene name EXO70
Aliases
Feature type ORF, Verified
Coordinates Chr X:272821..274692
Primary SGDID S000003621


Description of YJL085W: Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which directs secretory vesicles to active sites of exocytosis; acts with Sec3p in membrane targeting of the exocyst via PI(4,5)P2 binding[1][2][3]




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References

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  1. He B, et al. (2007) Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J 26(18):4053-65 SGD PMID 17717527
  2. TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 SGD PMID 8978675
  3. Robinson NG, et al. (1999) Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70. Mol Cell Biol 19(5):3580-7 SGD PMID 10207081

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