Difference between revisions of "YER030W"

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'''Description of YER030W:''' Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif<ref name='S000114561'>Begley TJ, et al. (2002) Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping. Mol Cancer Res 1(2):103-12 {{SGDpaper|S000114561}} PMID 12496357</ref><ref name='S000120727'>Luk E, et al. (2007) Chz1, a Nuclear Chaperone for Histone H2AZ. Mol Cell 25(3):357-68
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'''Description of YER030W:''' Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif<ref name='S000120727'>Luk E, et al. (2007) Chz1, a Nuclear Chaperone for Histone H2AZ. Mol Cell 25(3):357-68 {{SGDpaper|S000120727}} PMID 17289584</ref><ref name='S000114561'>Begley TJ, et al. (2002) Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping. Mol Cancer Res 1(2):103-12
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  {{SGDpaper|S000114561}} PMID 12496357</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YER030W
Gene name CHZ1
Aliases
Feature type ORF, Verified
Coordinates Chr V:213436..213897
Primary SGDID S000000832


Description of YER030W: Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif[1][2]




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References

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  1. Luk E, et al. (2007) Chz1, a Nuclear Chaperone for Histone H2AZ. Mol Cell 25(3):357-68 SGD PMID 17289584
  2. Begley TJ, et al. (2002) Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping. Mol Cancer Res 1(2):103-12 SGD PMID 12496357

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