Difference between revisions of "YGL020C"

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'''Description of YGL020C:''' Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance<ref name='S000127592'>Schuldiner M, et al. (2008) The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell 134(4):634-45 {{SGDpaper|S000127592}} PMID 18724936</ref><ref name='S000087084'>Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 {{SGDpaper|S000087084}} PMID 16269340</ref><ref name='S000071517'>Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
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'''Description of YGL020C:''' Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance<ref name='S000071517'>Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 {{SGDpaper|S000071517}} PMID 11907266</ref><ref name='S000087084'>Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 {{SGDpaper|S000087084}} PMID 16269340</ref><ref name='S000127592'>Schuldiner M, et al. (2008) The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell 134(4):634-45
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  {{SGDpaper|S000127592}} PMID 18724936</ref>
 
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Revision as of 04:15, 19 December 2008

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Systematic name YGL020C
Gene name GET1
Aliases MDM39
Feature type ORF, Verified
Coordinates Chr VII:457875..457168
Primary SGDID S000002988


Description of YGL020C: Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance[1][2][3]




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References

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  1. Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 SGD PMID 11907266
  2. Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 SGD PMID 16269340
  3. Schuldiner M, et al. (2008) The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell 134(4):634-45 SGD PMID 18724936

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