Difference between revisions of "YKL054C"
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| − | '''Description of YKL054C:''' RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis<ref name='S000124986'>Jordan PW, et al. (2007) Novel | + | '''Description of YKL054C:''' RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis<ref name='S000124986'>Jordan PW, et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222 {{SGDpaper|S000124986}} PMID 18069899</ref><ref name='S000086109'>Somesh BP, et al. (2005) Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest. Cell 121(6):913-23 {{SGDpaper|S000086109}} PMID 15960978</ref><ref name='S000069590'>Woudstra EC, et al. (2002) A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage. Nature 415(6874):929-33 |
{{SGDpaper|S000069590}} PMID 11859374</ref> | {{SGDpaper|S000069590}} PMID 11859374</ref> | ||
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Revision as of 14:05, 26 April 2008
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| Systematic name | YKL054C |
| Gene name | DEF1 |
| Aliases | VID31 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:338397..336181 |
| Primary SGDID | S000001537 |
Description of YKL054C: RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis[1][2][3]
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References
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- ↑ Jordan PW, et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222 SGD PMID 18069899
- ↑ Somesh BP, et al. (2005) Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest. Cell 121(6):913-23 SGD PMID 15960978
- ↑ Woudstra EC, et al. (2002) A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage. Nature 415(6874):929-33 SGD PMID 11859374
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