YOR332W

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Systematic name YOR332W
Gene name VMA4
Aliases
Feature type ORF, Verified
Coordinates Chr XV:943656..944357
Primary SGDID S000005859


Description of YOR332W: Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane[1][2]




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References

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  1. Foury F (1990) The 31-kDa polypeptide is an essential subunit of the vacuolar ATPase in Saccharomyces cerevisiae. J Biol Chem 265(30):18554-60 SGD PMID 2145285
  2. Ho MN, et al. (1993) Isolation of vacuolar membrane H(+)-ATPase-deficient yeast mutants; the VMA5 and VMA4 genes are essential for assembly and activity of the vacuolar H(+)-ATPase. J Biol Chem 268(1):221-7 SGD PMID 8416931

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