YMR073C

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Systematic name YMR073C
Gene name IRC21
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:412873..412268
Primary SGDID S000004677


Description of YMR073C: Putative protein of unknown function; may be involved in resistance to carboplatin and cisplatin; null mutant displays increase in spontaneous Rad52p foci; contains a lipid-binding domain and binds cardiolipin in a large-scale study[1][2][3]




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References

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  1. Alvaro D, et al. (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228 SGD PMID 18085829
  2. Gallego O, et al. (2010) A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol Syst Biol 6():430 SGD PMID 21119626
  3. Lee W, et al. (2005) Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. PLoS Genet 1(2):e24 SGD PMID 16121259

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