YBR211C

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Systematic name YBR211C
Gene name AME1
Aliases ARP100
Feature type ORF, Verified
Coordinates Chr II:647132..646158
Primary SGDID S000000415


Description of YBR211C: Essential kinetochore protein associated with microtubules and SPBs; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-U and fission yeast Mis17[1][2][3]




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References

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  1. De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 SGD PMID 14633972
  2. Pot I, et al. (2005) Spindle checkpoint maintenance requires Ame1 and Okp1. Cell Cycle 4(10):1448-56 SGD PMID 16177574
  3. Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13 SGD PMID 22561346

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