YKL206C

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Systematic name YKL206C
Gene name ADD66
Aliases PBA2, POC2
Feature type ORF, Verified
Coordinates Chr XI:49809..49006
Primary SGDID S000001689


Description of YKL206C: Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly[1][2]




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References

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  1. Li X, et al. (2007) beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J 26(9):2339-49 SGD PMID 17431397
  2. Scott CM, et al. (2007) ADD66, a Gene Involved in the Endoplasmic Reticulum-associated Degradation of {alpha}-1-Antitrypsin-Z in Yeast, Facilitates Proteasome Activity and Assembly. Mol Biol Cell 18(10):3776-87 SGD PMID 17634286

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