YPR161C
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| Systematic name | YPR161C | |
| Gene name | SGV1 | |
| Aliases | BUR1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:866418..864445 | |
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Description of YPR161C: Cyclin (Bur2p)-dependent protein kinase that functions in transcriptional regulation; phosphorylates the carboxy-terminal domain of Rpo21p, which is the largest subunit of RNA polymerase II; regulated by Cak1p[1][2][3][4][5]
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References
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- ↑ Keogh MC, et al. (2003) Bur1 kinase is required for efficient transcription elongation by RNA polymerase II. Mol Cell Biol 23(19):7005-18 SGD PMID 12972617
- ↑ Yao S and Prelich G (2002) Activation of the Bur1-Bur2 cyclin-dependent kinase complex by Cak1. Mol Cell Biol 22(19):6750-8 SGD PMID 12215532
- ↑ Murray S, et al. (2001) Phosphorylation of the RNA polymerase II carboxy-terminal domain by the Bur1 cyclin-dependent kinase. Mol Cell Biol 21(13):4089-96 SGD PMID 11390638
- ↑ Yao S, et al. (2000) BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo. Mol Cell Biol 20(19):7080-7 SGD PMID 10982824
- ↑ Prelich G and Winston F (1993) Mutations that suppress the deletion of an upstream activating sequence in yeast: involvement of a protein kinase and histone H3 in repressing transcription in vivo. Genetics 135(3):665-76 SGD PMID 8293972
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