Difference between revisions of "YPR068C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
Line 35: Line 35:
  
 
{{ShortCenteredHR}}
 
{{ShortCenteredHR}}
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
  
 
<protect>
 
<protect>

Revision as of 13:02, 21 February 2007

Share your knowledge...Edit this entry! <protect>

Systematic name YPR068C
Gene name HOS1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:684350..682938


Description of YPR068C: Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Protein Function/Process

In Robyr et al (2002), antibodies to specific acetyl forms of histones were used to find regions of the genome that increased in acetylation when certain histone deacetylases were deleted. Deletion of Hos1 resulted in increased acetylation primarily at the rDNA repeats. [2] [4]




<protect>

References

See Help:References on how to add references

  1. Davie JK, et al. (2003) Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo. J Biol Chem 278(50):50158-62 SGD PMID 14525981
  2. 2.0 2.1 Robyr D, et al. (2002) Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell 109(4):437-46 SGD PMID 12086601
  3. Rundlett SE, et al. (1996) HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc Natl Acad Sci U S A 93(25):14503-8 SGD PMID 8962081
  4. submitted by Hunter Fraser on 2003-04-18

See Help:Categories on how to add the wiki page for this gene to a Category </protect>