YPR048W

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Systematic name YPR048W
Gene name TAH18
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:659179..661050
Primary SGDID S000006252


Description of YPR048W: Protein of unknown function that plays a pro-death role in response to oxidative stress; highly conserved across species and similar to human protein NDOR1; allele is synthetically lethal with the pol3-13 allele of DNA polymerase delta[1][2][3]




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References

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  1. Chanet R and Heude M (2003) Characterization of mutations that are synthetic lethal with pol3-13, a mutated allele of DNA polymerase delta in Saccharomyces cerevisiae. Curr Genet 43(5):337-50 SGD PMID 12759774
  2. Vernis L, et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PLoS ONE 4(2):e4376 SGD PMID 19194512
  3. Heinicke S, et al. (2007) The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. PLoS ONE 2(1):e766 SGD PMID 17712414

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