YPR048W

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Systematic name YPR048W
Gene name TAH18
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:659182..661053
Primary SGDID S000006252


Description of YPR048W: Conserved NAPDH-dependent diflavin reductase, component of an early step in the cytosolic Fe-S protein assembly (CIA) machinery; transfers electrons from NADPH to the Fe-S cluster of Dre2p; plays a pro-death role under oxidative stress[1][2]




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References

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  1. Netz DJ, et al. (2010) Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis. Nat Chem Biol 6(10):758-65 SGD PMID 20802492
  2. Vernis L, et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PLoS ONE 4(2):e4376 SGD PMID 19194512

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