Difference between revisions of "YPR048W"
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| − | '''Description of YPR048W:''' Protein of unknown function; highly conserved across species and similar to human protein NDOR1 | + | '''Description of YPR048W:''' Protein of unknown function that plays a pro-death role in response to oxidative stress; highly conserved across species and similar to human protein NDOR1; allele is synthetically lethal with the pol3-13 allele of DNA polymerase delta<ref name='S000073937'>Chanet R and Heude M (2003) Characterization of mutations that are synthetic lethal with pol3-13, a mutated allele of DNA polymerase delta in Saccharomyces cerevisiae. Curr Genet 43(5):337-50 {{SGDpaper|S000073937}} PMID 12759774</ref><ref name='S000129193'>Vernis L, et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PLoS ONE 4(2):e4376 {{SGDpaper|S000129193}} PMID 19194512</ref><ref name='S000123894'>Heinicke S, et al. (2007) The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. PLoS ONE 2(1):e766 |
{{SGDpaper|S000123894}} PMID 17712414</ref> | {{SGDpaper|S000123894}} PMID 17712414</ref> | ||
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Revision as of 14:05, 23 April 2009
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| Systematic name | YPR048W |
| Gene name | TAH18 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:659179..661050 |
| Primary SGDID | S000006252 |
Description of YPR048W: Protein of unknown function that plays a pro-death role in response to oxidative stress; highly conserved across species and similar to human protein NDOR1; allele is synthetically lethal with the pol3-13 allele of DNA polymerase delta[1][2][3]
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References
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- ↑ Chanet R and Heude M (2003) Characterization of mutations that are synthetic lethal with pol3-13, a mutated allele of DNA polymerase delta in Saccharomyces cerevisiae. Curr Genet 43(5):337-50 SGD PMID 12759774
- ↑ Vernis L, et al. (2009) A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PLoS ONE 4(2):e4376 SGD PMID 19194512
- ↑ Heinicke S, et al. (2007) The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. PLoS ONE 2(1):e766 SGD PMID 17712414
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