Difference between revisions of "YPL127C"
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| − | '''Description of YPL127C:''' Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation<ref name=' | + | '''Description of YPL127C:''' Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation<ref name='S000073592'>Downs JA, et al. (2003) Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. Mol Cell 11(6):1685-92 {{SGDpaper|S000073592}} PMID 12820979</ref><ref name='S000054174'>Escher D and Schaffner W (1997) Gene activation at a distance and telomeric silencing are not affected by yeast histone H1. Mol Gen Genet 256(4):456-61 {{SGDpaper|S000054174}} PMID 9393443</ref><ref name='S000065991'>Freidkin I and Katcoff DJ (2001) Specific distribution of the Saccharomyces cerevisiae linker histone homolog HHO1p in the chromatin. Nucleic Acids Res 29(19):4043-51 {{SGDpaper|S000065991}} PMID 11574687</ref><ref name='S000062790'>Hellauer K, et al. (2001) Decreased expression of specific genes in yeast cells lacking histone H1. J Biol Chem 276(17):13587-92 {{SGDpaper|S000062790}} PMID 11278859</ref><ref name='S000063502'>Landsman D (1996) Histone H1 in Saccharomyces cerevisiae: a double mystery solved? Trends Biochem Sci 21(8):287-8 {{SGDpaper|S000063502}} PMID 8772381</ref><ref name='S000043555'>Patterton HG, et al. (1998) The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae. J Biol Chem 273(13):7268-76 {{SGDpaper|S000043555}} PMID 9516420</ref><ref name='S000045120'>Puig S, et al. (1999) Stochastic nucleosome positioning in a yeast chromatin region is not dependent on histone H1. Curr Microbiol 39(3):168-72 {{SGDpaper|S000045120}} PMID 10441732</ref><ref name='S000041152'>Ushinsky SC, et al. (1997) Histone H1 in Saccharomyces cerevisiae. Yeast 13(2):151-61 |
| − | {{SGDpaper| | + | {{SGDpaper|S000041152}} PMID 9046096</ref> |
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Revision as of 14:05, 25 February 2010
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL127C |
| Gene name | HHO1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:309603..308827 |
| Primary SGDID | S000006048 |
Description of YPL127C: Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation[1][2][3][4][5][6][7][8]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Strain Background: S288c
Genotype: BQS238: MATalfa, ura3-52, leu2-3,112, ade2-101, suc2-delta9, gal2, hho1delta0, pRB58
Phenotype(s): No Phenotype, Deletion of HHO1 has no effect on nucleosome positioning, Viable
Hho1p has no effect on nucleosome positioning in yeast. [7] [9]
DNA and RNA Details
Other DNA and RNA Details
Other Topic: Nucleosome positioning
We analyzed a chromatin region of the yeast Chromosome (Chr) IX, in which there are two closely packed open reading frames (ORFs), POT1 and YIL161w. This locus shows a regular ladder of 13 stochastically positioned nucleosomes, which is unaffected by the absence of the HHO1 gene. This suggests that histone H1 has no effect on nucleosome positioning in yeast. [7] [9]
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References
See Help:References on how to add references
- ↑ Downs JA, et al. (2003) Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. Mol Cell 11(6):1685-92 SGD PMID 12820979
- ↑ Escher D and Schaffner W (1997) Gene activation at a distance and telomeric silencing are not affected by yeast histone H1. Mol Gen Genet 256(4):456-61 SGD PMID 9393443
- ↑ Freidkin I and Katcoff DJ (2001) Specific distribution of the Saccharomyces cerevisiae linker histone homolog HHO1p in the chromatin. Nucleic Acids Res 29(19):4043-51 SGD PMID 11574687
- ↑ Hellauer K, et al. (2001) Decreased expression of specific genes in yeast cells lacking histone H1. J Biol Chem 276(17):13587-92 SGD PMID 11278859
- ↑ Landsman D (1996) Histone H1 in Saccharomyces cerevisiae: a double mystery solved? Trends Biochem Sci 21(8):287-8 SGD PMID 8772381
- ↑ Patterton HG, et al. (1998) The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae. J Biol Chem 273(13):7268-76 SGD PMID 9516420
- ↑ 7.0 7.1 7.2 Puig S, et al. (1999) Stochastic nucleosome positioning in a yeast chromatin region is not dependent on histone H1. Curr Microbiol 39(3):168-72 SGD PMID 10441732
- ↑ Ushinsky SC, et al. (1997) Histone H1 in Saccharomyces cerevisiae. Yeast 13(2):151-61 SGD PMID 9046096
- ↑ 9.0 9.1 submitted by Jose E. Perez-Ortin on 2004-05-27
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
Categories:
- ORF
- ORF, Verified
- Topic:Alleles, Strains, and Phenotypes
- Topic:Alleles, Strains, and Phenotypes:Complete Deletion
- Phenotype:No Phenotype
- Phenotype:Deletion of HHO1 has no effect on nucleosome positioning
- Phenotype:Viable
- Topic:DNA and RNA Details
- Topic:DNA and RNA Details:Other DNA and RNA Details
- Topic:Nucleosome positioning
