Difference between revisions of "YOR197W"
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| − | '''Description of YOR197W:''' Putative cysteine protease similar to mammalian caspases; involved in regulation of apoptosis upon | + | '''Description of YOR197W:''' Putative cysteine protease similar to mammalian caspases; involved in regulation of apoptosis upon H2O2 treatment; contributes to clearance of insoluble protein aggregates during normal growth; may be involved in cell cycle progression<ref name='S000127360'>Lee RE, et al. (2008) A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics. PLoS ONE 3(8):e2956 {{SGDpaper|S000127360}} PMID 18698411</ref><ref name='S000135026'>Lee RE, et al. (2010) Metacaspase Yca1 is required for clearance of insoluble protein aggregates. Proc Natl Acad Sci U S A 107(30):13348-53 {{SGDpaper|S000135026}} PMID 20624963</ref><ref name='S000070033'>Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 |
{{SGDpaper|S000070033}} PMID 11983181</ref> | {{SGDpaper|S000070033}} PMID 11983181</ref> | ||
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Revision as of 14:05, 11 February 2011
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| Systematic name | YOR197W |
| Gene name | MCA1 |
| Aliases | YCA1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:717086..718384 |
| Primary SGDID | S000005723 |
Description of YOR197W: Putative cysteine protease similar to mammalian caspases; involved in regulation of apoptosis upon H2O2 treatment; contributes to clearance of insoluble protein aggregates during normal growth; may be involved in cell cycle progression[1][2][3]
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References
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- ↑ Lee RE, et al. (2008) A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics. PLoS ONE 3(8):e2956 SGD PMID 18698411
- ↑ Lee RE, et al. (2010) Metacaspase Yca1 is required for clearance of insoluble protein aggregates. Proc Natl Acad Sci U S A 107(30):13348-53 SGD PMID 20624963
- ↑ Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 SGD PMID 11983181
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