YOR109W
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| Systematic name | YOR109W |
| Gene name | INP53 |
| Aliases | SJL3, SOP2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:525279..528602 |
Description of YOR109W: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in a TGN (trans Golgi network)-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches[1][2][3][4]
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References
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- ↑ Ha SA, et al. (2003) The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell 14(4):1319-33 SGD PMID 12686590
- ↑ Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2():337-52 SGD PMID 10947947
- ↑ Ooms LM, et al. (2000) The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Mol Cell Biol 20(24):9376-90 SGD PMID 11094088
- ↑ Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 SGD PMID 10224048
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