From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YOR109W
Gene name INP53
Aliases SJL3, SOP2
Feature type ORF, Verified
Coordinates Chr XV:525278..528601
Primary SGDID S000005635

Description of YOR109W: Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains[1][2][3][4]


Community Commentary

About Community Commentary. Please share your knowledge!



See Help:References on how to add references

  1. Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 SGD PMID 10224048
  2. Ha SA, et al. (2003) The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell 14(4):1319-33 SGD PMID 12686590
  3. Hughes WE, et al. (2000) Sac phosphatase domain proteins. Biochem J 350 Pt 2():337-52 SGD PMID 10947947
  4. Ooms LM, et al. (2000) The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Mol Cell Biol 20(24):9376-90 SGD PMID 11094088

See Help:Categories on how to add the wiki page for this gene to a Category </protect>