Difference between revisions of "YOR028C"

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'''Description of YOR028C:''' Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus<ref name='S000060008'>Furuchi T, et al. (2001) Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae. Mol Pharmacol 59(3):470-4 {{SGDpaper|S000060008}} PMID 11179441</ref><ref name='S000045640'>Mendizabal I, et al. (1998) Yeast putative transcription factors involved in salt tolerance. FEBS Lett 425(2):323-8
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'''Description of YOR028C:''' Basic leucine zipper (bZIP) transcription factor of the yAP-1 family, mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions<ref name='S000128470'>Sollner S, et al. (2009) Quinone reductase acts as a redox switch of the 20S yeast proteasome. EMBO Rep 10(1):65-70 {{SGDpaper|S000128470}} PMID 19029946</ref><ref name='S000060008'>Furuchi T, et al. (2001) Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae. Mol Pharmacol 59(3):470-4 {{SGDpaper|S000060008}} PMID 11179441</ref><ref name='S000045640'>Mendizabal I, et al. (1998) Yeast putative transcription factors involved in salt tolerance. FEBS Lett 425(2):323-8
 
  {{SGDpaper|S000045640}} PMID 9559673</ref>
 
  {{SGDpaper|S000045640}} PMID 9559673</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YOR028C
Gene name CIN5
Aliases HAL6, YAP4
Feature type ORF, Verified
Coordinates Chr XV:384420..383533
Primary SGDID S000005554


Description of YOR028C: Basic leucine zipper (bZIP) transcription factor of the yAP-1 family, mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions[1][2][3]




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References

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  1. Sollner S, et al. (2009) Quinone reductase acts as a redox switch of the 20S yeast proteasome. EMBO Rep 10(1):65-70 SGD PMID 19029946
  2. Furuchi T, et al. (2001) Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae. Mol Pharmacol 59(3):470-4 SGD PMID 11179441
  3. Mendizabal I, et al. (1998) Yeast putative transcription factors involved in salt tolerance. FEBS Lett 425(2):323-8 SGD PMID 9559673

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