Difference between revisions of "YNL330C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005274 YNL330C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RPD3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RPD3 '' | ||
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|nowrap| Chr XIV:19302..18001 | |nowrap| Chr XIV:19302..18001 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005274 |
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| − | '''Description of | + | '''Description of YNL330C:''' Histone deacetylase; regulates transcription, silencing, and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members<ref name='S000113735'>Carrozza MJ, et al. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123(4):581-92 {{SGDpaper|S000113735}} PMID 16286007</ref><ref name='S000130224'>Knott SR, et al. (2009) Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae. Genes Dev 23(9):1077-90 {{SGDpaper|S000130224}} PMID 19417103</ref><ref name='S000131555'>Kremer SB and Gross DS (2009) SAGA and Rpd3 Chromatin Modification Complexes Dynamically Regulate Heat Shock Gene Structure and Expression. J Biol Chem 284(47):32914-31 {{SGDpaper|S000131555}} PMID 19759026</ref><ref name='S000125260'>Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 {{SGDpaper|S000125260}} PMID 18202368</ref><ref name='S000133875'>Ruiz-Roig C, et al. (2010) The Rpd3L HDAC complex is essential for the heat stress response in yeast. Mol Microbiol 76(4):1049-62 {{SGDpaper|S000133875}} PMID 20398213</ref><ref name='S000047708'>Rundlett SE, et al. (1996) HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc Natl Acad Sci U S A 93(25):14503-8 {{SGDpaper|S000047708}} PMID 8962081</ref><ref name='S000129959'>Zhou J, et al. (2009) Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation. Nucleic Acids Res 37(11):3699-713 |
| − | {{SGDpaper| | + | {{SGDpaper|S000129959}} PMID 19372273</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL330C |
| Gene name | RPD3 |
| Aliases | MOF6, REC3, SDI2, SDS6 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:19302..18001 |
| Primary SGDID | S000005274 |
Description of YNL330C: Histone deacetylase; regulates transcription, silencing, and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members[1][2][3][4][5][6][7]
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Contents
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References
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- ↑ Carrozza MJ, et al. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123(4):581-92 SGD PMID 16286007
- ↑ Knott SR, et al. (2009) Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae. Genes Dev 23(9):1077-90 SGD PMID 19417103
- ↑ Kremer SB and Gross DS (2009) SAGA and Rpd3 Chromatin Modification Complexes Dynamically Regulate Heat Shock Gene Structure and Expression. J Biol Chem 284(47):32914-31 SGD PMID 19759026
- ↑ Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368
- ↑ Ruiz-Roig C, et al. (2010) The Rpd3L HDAC complex is essential for the heat stress response in yeast. Mol Microbiol 76(4):1049-62 SGD PMID 20398213
- ↑ Rundlett SE, et al. (1996) HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc Natl Acad Sci U S A 93(25):14503-8 SGD PMID 8962081
- ↑ Zhou J, et al. (2009) Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation. Nucleic Acids Res 37(11):3699-713 SGD PMID 19372273
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