Difference between revisions of "YNL049C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004994 YNL049C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004994 YNL049C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SFB2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SFB2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIV:537912..535282
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|nowrap| Chr XIV:537911..535281
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004994
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004994
 
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'''Description of YNL049C:''' Probable component of COPII coated vesicles that binds to Sec23p; similar to and functionally redundant with Sec24p, but expressed at low levels; involved in ER to Golgi transport and in autophagy<ref name='S000052357'>Peng R, et al. (2000) Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members. J Biol Chem 275(15):11521-8 {{SGDpaper|S000052357}} PMID 10753972</ref><ref name='S000074058'>Hamasaki M, et al. (2003) The early secretory pathway contributes to autophagy in yeast. Cell Struct Funct 28(1):49-54
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'''Description of YNL049C:''' Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb3p<ref name='S000052326'>Kurihara T, et al. (2000) Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae. Mol Biol Cell 11(3):983-98 {{SGDpaper|S000052326}} PMID 10712514</ref><ref name='S000074170'>Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509 {{SGDpaper|S000074170}} PMID 12941277</ref><ref name='S000052357'>Peng R, et al. (2000) Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members. J Biol Chem 275(15):11521-8
  {{SGDpaper|S000074058}} PMID 12655150</ref>
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  {{SGDpaper|S000052357}} PMID 10753972</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YNL049C
Gene name SFB2
Aliases ISS1
Feature type ORF, Verified
Coordinates Chr XIV:537911..535281
Primary SGDID S000004994


Description of YNL049C: Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb3p[1][2][3]




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References

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  1. Kurihara T, et al. (2000) Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae. Mol Biol Cell 11(3):983-98 SGD PMID 10712514
  2. Miller EA, et al. (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509 SGD PMID 12941277
  3. Peng R, et al. (2000) Evidence for overlapping and distinct functions in protein transport of coat protein Sec24p family members. J Biol Chem 275(15):11521-8 SGD PMID 10753972

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